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<span style="font-size: 10pt; font-family: Arial;" data-sheets-root="1">Sublocade, a medication used for opioid dependence, can stay in your system for several weeks. It releases buprenorphine slowly, providing long-lasting effects that support recovery. Typically, traces can remain detectable for up to two months after the last injection.</span>How Long Does Sublocade Stay In Your System?