Intestinal worms can be treated safely by targeting parasites while minimizing human toxicity. Modern anthelmintics disrupt worm metabolism or microtubules, which humans tolerate at therapeutic levels. Medications such as benzimidazoles are widely used under medical supervision, alongside hygiene measures to prevent reinfection. Proper diagnosis, weight-appropriate prescribing, and adherence to guidance reduce side effects. Avoid unverified remedies and never self-dose. Supportive steps include handwashing, safe food handling, clean water, and laundering bedding. For public health programs, sourcing quality-controlled medicines, including mebendazole wholesale supplies, helps ensure efficacy and safety while protecting communities, through training, monitoring, reporting, access, equity, stewardship, compliance, surveillance, evaluation.